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. 2020 Nov 26;13(12):424. doi: 10.3390/ph13120424

Figure 4.

Figure 4

Intracellular signaling pathways activated by EPO/EPOR system. EPO molecule activates different intracellular pathways through EPOR, leading to anti-apoptotic gene expression as well as the inhibition of pro-apoptosis genes. These actions allow for cell proliferation, differentiation and cell survival against the pathological stimulus generated by Aβ and tau-p protein in AD.