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. 2020 Nov 26;12(12):3525. doi: 10.3390/cancers12123525

Table 1.

Different synthetic methods and the characteristics of the products obtained.

Method Size Morphology Magnetization (Emu/g) Ligand Surface Groups Used Supplier Photos Reference
Co-precipitation 30–1000 nm Roughly spherical - Dextran −OH Miltenyi biotec (MACS) Inline graphic(A) [34,35]
100 nm Irregular shape - BSA −NH2−COOH Veridex Ferrofluid™ Inline graphic(B) [29]
1.0/2.8/4.5 μm Spherical 10.8–23.5 Polymer −NH2 InvitrogenTM
Dynal
Inline graphic(C) [36]
Thermal decomposition 20.3 ± 1.5 nm Spherical 85.8 PEG −COOH N/A Inline graphic(D) [37]
30 nm Spherical - ABC triblock copolymer −COOH N/A Inline graphic(E) [38]
Solvothermal 80 nm Spherical nanocluster 80 leukocyte membrane Hydro-phobic inter-action N/A Inline graphic(F) [39]
100–300 nm Spherical nanocluster 58.48 Silica −OH AMO LIFESCIENCE Inc., Korea Inline graphic(G) [40]
Microemulsion 10 nm Spherical 33.2 Oleyla-mine −NH2 N/A Inline graphic(H) [41]

Picture (C) reprinted with permission from [36]; Picture (D) reprinted with permission from [37]; Picture (E) reprinted with permission from [38]; Picture (F) reprinted with permission from [39]; Picture (G) reprinted with permission from [40]; Picture (H) reprinted with permission from [41].