Figure 7.
Differential expression of proteins between tissue compartments. Paired t-tests with a Benjamini–Hochberg correction were performed between matched compartments. Mann–Whitney tests with Benjamini–Hochberg correction were performed between unmatched compartments; p-values adjusted for multiple testing were used to identify significantly differentially expressed proteins. (A) NAT–TME (n = 8), (B) TME–tumour (n = 18), (C) NAT (n = 19) vs. TME (n = 32); (D) TME (n = 32) vs. tumour (n = 45). NAT: normal adjacent tissue; TME: tumour microenvironment; tumour: tumour region.