Table 1.
Demographics and clinical characteristics of patients with optic neuritis and healthy controls.
| Optic Neuritis (n = 48 Eyes) |
Control (n = 48 Eyes) |
|
|---|---|---|
| Gender (Male/female) 1 | 13 (35%)/24 (65%) | 23 (48%)/25 (52%) |
| Age 2 | 39 ± 14 (20,66) | 40 ± 12 (23,64) |
| SE 2 | −1.3 ± 2.0 (−5.8–1.13) | −0.9 ± 1.6 (−4.8–1.6) |
| Initial visual acuity (LogMAR) | 1.20 ± 1.26 (0–3) | 0 ± 0.02 (0–0.09) |
| Follow-up period (months) | 11 ± 3 (6–15) | |
| NMO-IgG Ab (−/+) | 28 (58%)/20 (42%) | |
| Disc swelling (−/+) | 18 (38%)/30 (62%) | |
| Low visual acuity 3 | 18 (38%) | |
| Worse visual field 4 | 16 (33%) |
1 The gender distribution was compared using the chi-square test and found to be statistically insignificant (p = 0.668). 2 The Mann-Whitney U test was used to compare age and SE between two groups; the differences between groups were found to be statistically insignificant (p = 0. 350, p = 0.461, respectively). 3 Low visual acuity refers to an initial visual acuity of 20/200 or worse. 4 Worse visual field function is indicated by MD values of −10 dB or less at the final visit. SE: Spherical equivalent; LogMAR: logarithmic scale; NMO-IgG Ab: neuromyelitis optica-immunoglobulin G antibody.