Table 1.
Effect of BPA on serum biochemical parameters and adipokine profile in HFD mice.
| Serum Parameters | STD | HFD | HFD + BPA |
|---|---|---|---|
| ALT (U/L) | 65.0 ± 2.12 | 139.2 ± 4.03 **** | 183.2 ± 3.16 #### |
| ALP (U/L) | 155.0 ± 3.44 | 265.6 ± 4.58 **** | 288.2 ± 6.41 # |
| Triglycerides (mg/dL) | 114.6 ± 5.391 | 218.6 ± 6.87 **** | 258.3 ± 6.86 ## |
| MCP-1 (pg/mL) | 28.50 ± 1.28 | 61.0 ± 2.00 **** | 74.6 ± 3.55 ## |
| LPS (U/mL) | 0.62 ± 0.02 | 1.53 ± 0.02 **** | 1.84 ± 0.04 ## |
| IL-10 (ng/mL) | 0.044 ± 0.002 | 0.034 ± 0.003 * | 0.019 ± 0.001 ## |
| Leptin (ng/mL) | 1.08 ± 0.04 | 12.88 ± 0.36 **** | 15.65 ± 0.42 ### |
| Adiponectin (mg/mL) | 2.87 ± 0.09 | 1.26 ± 0.06 **** | 1.07 ± 0.07 **** |
| Lep/Adipo ratio | 0.38 ± 0.02 | 9.63 ± 0.08 **** | 15.59 ± 0.81 #### |
Data are presented as mean ± SEM of all animals from different groups (n = 6–8) (* p < 0.05, **** p < 0.0001 vs. STD; # p < 0.05, ## p < 0.01, ### p < 0.001, #### p < 0.0001 vs. HFD. Abbreviations: ALT, alanine aminotransferase; ALP, alkaline phosphatase; MCP-1, monocyte chemoattractant protein 1; LPS, lipopolysaccharide; IL-10, interleukin-10.