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. 2020 Nov 28;8(12):1885. doi: 10.3390/microorganisms8121885

Figure 1.

Figure 1

Convalescent plasma donors anti-SARS-CoV-2 antibodies against all studied epitopes on the day of screening, according to disease severity (A–D). The median ratio (IQR) for anti-S1-IgG antibodies using the Euroimmun ELISA method were as follows: 1.69 (2.59) vs. 4.40 (5.42) vs. 8.04 (4.69) for asymptomatic, non-hospitalized symptomatic and hospitalized symptomatic, respectively (p = 0.0001, Kruskal–Wallis test); (A) the respective values of the median fluorescent intensity (IQR) for the total (IgM+IgA+IgG) antibodies, using the multiplex assay, against basic nucleocapsid (N) protein were: 18,875 (38,803) vs. 48,703 (30,981) vs. 60,913 (12,810) (p = 0.0001; (B) while against S1 were 22,806 (26,735) vs. 40,436 (27,514) vs. 58,377 (15,733) (p = 0.002)); (C) and against receptor-binding domain (RBD) were 21,515 (24,077) vs. 38,556 (26,393) vs. 55,869 (14,522) (p = 0.002; (D)).