Table 1.
Demographic characteristics of the study cohort.
| Variable | Without PH | With PH | Severe PH | p-Value |
|---|---|---|---|---|
| (n = 188) | (n = 96) | (n = 56) | ||
| Age | 55.8 ± 15.6 | 60.2 ± 14.3 | 59.3 ± 14.3 | 0.042 |
| Male sex | 93 (49.5) | 36 (37.5) | 25 (44.6) | 0.158 |
| Ever smoker | 46 (24.4) | 17 (17.7) | 17 (30.3) | 0.187 |
| Follow-up duration, months | 42.7 ± 38.5 | 40.8 ± 37.8 | 41.7 ± 37.5 | 0.921 |
| BMI, kg/m2 | 28.9 ± 6.3 | 30.1 ± 6.6 | 30.4 ± 8.4 | 0.202 |
| Underlying disease | ||||
| IPF | 59 (31.3) | 34 (35.4) | 22 (39.2) | 0.508 |
| CTD-ILD | 70 (37.2) | 39 (40.6) | 20 (35.7) | 0.798 |
| Rheumatoid arthritis | 13 (6.9) | 4 (4.1) | 1 (1.7) | 0.272 |
| SLE | 5 (2.6) | 3 (3.1) | 1 (1.7) | 0.884 |
| Systemic sclerosis | 8 (4.2) | 9 (9.3) | 0 | 0.030 |
| Primary Sjogren’s syndrome | 10 (5.3) | 13 (13.5) | 7 (12.5) | 0.039 |
| Polymyositis | 3 (1.5) | 0 | 1 (1.7) | 0.448 |
| MCTD | 11 (5.8) | 2 (2.0) | 2 (3.5) | 0.324 |
| UCTD | 20 (10.6) | 8 (8.3) | 8 (14.2) | 0.516 |
| Sarcoidosis | 26 (13.8) | 11 (11.4) | 11 (19.6) | 0.371 |
| Chronic Hypersensitivity Pneumonitis | 14 (7.4) | 5 (5.2) | 1 (1.7) | 0.272 |
| Idiopathic NSIP | 4 (2.1) | 4 (4.1) | 2 (3.5) | 0.601 |
| Others | ||||
| Organizing Pneumonia | 4 (2.1) | 2 (2.0) | 0 | 0.547 |
| Unclassifiable fibrosis | 6 (3.1) | 0 | 0 | 0.085 |
| RBILD | 3 (1.5) | 1 (1.0) | 0 | 0.617 |
| DIP | 2 (1.0) | 0 | 0 | 0.443 |
Data are presented as the means ± standard deviations or numbers (percentages). PH: pulmonary hypertension; BMI: body mass index; IPF: idiopathic pulmonary fibrosis; CTD: connective tissue disease; ILD: interstitial lung disease; SLE: systemic lupus erythematosus; MCMCTD: mixed connective tissue disease; UCTD: undifferentiated connective tissue disease; NSIP: nonspecific interstitial pneumonia; RBILD: respiratory bronchiolitis interstitial lung disease; DIP: desquamative interstitial pneumonia.