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. 2020 Nov 27;12(12):1155. doi: 10.3390/pharmaceutics12121155

Table 2.

The effective concentrations of antimicrobials resulting in a 50% decrease in cell amount (EC50, pg.cell−1) in the absence or presence of quorum-quenching (QQ) enzymes loaded onto bacterial cellulose (BC) samples.

G(+) Bacterial Cells: Bacillus subtilis B-522
QQ Enzyme Colistin Polymyxin B Indolicidin Temporin A
None 6.16 ± 0.19 5.13 ± 0.16 66.72 ± 0.43 7.90 ± 0.06
His6-OPH 1.41 ± 0.03 0.38 ± 0.01 12.24 ± 0.23 5.31 ± 0.01
Penicillin acylase 0.47 ± 0.03 0.21 ± 0.01
Thermolysin 614 ± 13 364 ± 12
Carboxypeptidase A 14,166 ± 94 1684 ± 53
G(−) Bacterial Cells: Pseudomonas sp. 78G
None 4.61 ± 0.22 4.35 ± 0.11 6.93 ± 0.18 2.24 ± 0.03
His6-OPH 0.13 ± 0.02 1.16 ± 0.16 2.61 ± 0.24 1.18 ± 0.02
Penicillin acylase 0.37 ± 0.02 0.97 ± 0.02
Thermolysin 17.28 ± 0.49 3.14 ± 0.32
Carboxypeptidase A 7.05 ± 0.19 33.28 ± 1.39