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. 2020 Nov 25;12(12):1141. doi: 10.3390/pharmaceutics12121141

Table 1.

Values of the correlation coefficients (r2) and drug release rate constant (k) obtained by fitting ibuprofen or fenofibrate release data from NE1 and NE2 with zero-order, first-order and square of time release mathematical models.

Zero Order First Order √t
r2 k (mgh−1) r2 k (h−1) r2 k (mgh−1/2)
Ibuprofen NE1 0.9539 0.823 0.7157 1.286 0.9105 1.198
NE2 0.9017 0.980 0.8098 0.661 0.9868 1.530
Fenofibrate NE1 0.9304 0.021 0.608 0.058 0.9917 0.158
NE2 0.9112 0.022 0.7632 0.069 0.9991 0.124