Table 2.

Uni- and multi-variate logistic regression analysis. Risk factors for mortality within the CytoSorb group.

	Crude Odds Ratio (95% CI)	p	Adjusted Odds Ratio (95% CI)	p
Age (per year)	1.08 (1.02–1.15)	0.009	1.09 (0.97–1.22)	0.164
Female Gender	0.85 (0.23–3.21)	0.81
Sepsis source			7.86 (0.94–65.59)	0.057
Abdominal	11.00 (2.42–49.91)	0.002
Pulmonal	0.34 (0.08–1.51)	0.156
Urogenital	2.00 (0.12–34.6)	0.634
Soft tissue	1.20 (0.24–5.97)	0.824
Suspected pathogen
Gram negative bacteria	reference
Gram positive bacteria	0.53 (0.12–2.27)	0.390
Comorbidities (any)	4.00 (0.43–36.92)	0.221
Arterial hypertension	7.00 (0.79–61.97)	0.080
Cerebrovascular disease	1.10 (0.22–5.42)	0.907
COPD	6.50 (0.61–69.14)	0.121
Coronary artery disease	3.27 (0.86–12.35)	0.081
Diabetes mellitus type 2	1.09 (0.31–3.88)	0.890
Heart failure	1.44 (0.28–7.5)	0.667
Chronic kidney disease	4.29 (1.12–16.44)	0.034
Peripheral artery disease	>99 (0–∞)	0.992	1.46 (0.16–13.52)	0.741
Baseline characteristics
SOFA Score (per point)	1.57 (1.07–2.3)	0.02
PaO2/FiO2 (per mmHg)	1.00 (0.99–1.00)	0.757
Norepinephrine (per µg/kg/min) *	0.70 (0.09–5.59)	0.737
Bilirubin (per mg/dL)	1.15 (0.87–1.51)	0.334
Thrombocytes (per G/L)	0.98 (0.97–1.00)	0.015	0.98 (0.96–1.00)	0.049
Procalcitonin (per µg/L)	1.00 (0.99–1.00)	0.287
Lactate (per mmol/L)	1.21 (1.03–1.43)	0.019	1.27 (1.00–1.60)	0.045

* displayed as norepinephrine equivalents (in accordance to [41]).