Figure 5.

Correlation with regression line for gene expression (in units if log2(norm_count + 1)) for XIST vs. TSIX, Spearman’s rank correlation test was used to generate the correlation coefficient represented as R in the analyses, p represents p-value. Healthy lung, LUAD, and LUSC were compared separately in both sexes. Total sample number is 1299, 794 derived from male patients and 505 from female patients. There are 116 samples from male patients with 0 expression in XIST, 461 in TSIX. In female patients derived samples, 17 show zero expression for TSIX gene. All samples with zero expression in both genes were removed from the analysis.