Table 4.
Mean content of sesquiterpene lactones detected in active or heat-inactivated fecal suspensions incubated with Brussels/witloof chicory a.
| Compound (nmol) | Incubation Time (h) with Active Fecal Suspensions |
Incubation Time (h) with Heat-Inactivated Fecal Suspensions |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 0.5 | 1 | 2 | 24 | 0 | 0.5 | 1 | 2 | 24 | |
| LAC | 50.4 ± 2.84 |
89.0 ± 14.6 * |
147 ± 32.7 * |
211 ± 64.1 * |
159 ± 43.0 * |
48.3 ± 2.07 |
42.0 ± 7.49 |
46.3 ± 6.82 |
42.2 ± 6.07 |
45.0 ± 10.3 |
| DLAC | 158 ± 7.43 |
274 ± 46.1 * |
435 ± 111 * |
514 ± 132 * |
384 ± 91.1 * |
154 ± 5.52 |
143 ± 24.4 |
157 ± 41.61 |
141 ± 13.6 |
135.47 ± 19.3 |
| LCP | 211 ± 13.3 |
183 ± 28.9 |
127 ± 20.6 * |
ND | ND | 200 ± 10.2 |
209 ± 17.7 |
184 ± 29.4 |
199 ± 31.6 |
204 ± 27.8 |
| DLCP | 17.2 ± 1.14 |
9.76 ± 1.67 * |
4.37 ± 1.04 * |
ND | ND | 18.1 ± 0.98 |
16.5 ±1.53 |
16.3 ± 1.28 |
16.6 ± 4.12 |
17.3 ± 3.61 |
| LAC-Gly | 46.1 ± 3.77 |
37.8 ± 4.57 |
13.2 ± 5.93 * |
ND | ND | 48.2 ± 2.9 |
44.9 ± 9.47 |
42.6 ± 9.78 |
39.7 ± 8.58 |
42.0 ± 5.68 |
| DLAC-Gly | 249 ± 18.0 |
184 ± 26.0 * |
57.2 ± 17.8 * |
ND | ND | 238 ± 15.78 |
226 ± 29.2 |
219 ± 25.5 |
209 ± 46 |
205 ± 43.2 |
| LCP-Gly | 153 ± 9.13 |
55.1 ± 14.1 * |
9.91 ± 2.1* |
ND | ND | 149 ± 12.0 |
134 ± 25.6 |
124 ± 20.0 |
128 ± 15.3 |
127 ± 26.9 |
| DLCP-Gly | 9.04 ± 1.07 |
5.67 ± 1.19 * |
1.47 ± 0.75 * |
ND | ND | 9.2 ± 1.13 |
8.46 ± 1.35 |
8.04 ± 1.21 |
8.19 ± 1.14 |
7.84 ± 1.36 |
a Values are the means ± SEM, n = 5; LAC, lactucin; DLAC, 11β,13-dihydrolactucin; LCP, lactucopicrin; DLCP, 11β,13-dihydrolactucopicrin; Gly, glycosylated form; ND, not detected. * p < 0.05 compared with the T0 groups.