Table 3.
Association between MRI parameters and histological inflammation score
| Histological inflammation score |
|||||
|---|---|---|---|---|---|
| MRI parameters | Mild (n=20) | Moderate (n=44) | Severe (n=18) | P | |
| MT ratio, mean ± SD (range) | 29.85±7.43 (19.12–40.93) |
37.68±6.46 (21.53–50.79) |
35.87±7.46 (19.10–48.12) |
0.002 b | |
| Wall thickness, mean ± SD (range) | 5.35±2.39 (2.50–10.40) |
10.81±3.31 (3.31–22.80) |
11.11±3.40 (6.73–18.40) |
<0.001 b | |
| High signal intensity on T2WI | 4 (20.0%) | 39 (88.6%) | 15 (83.3%) | <0.001 a | |
| Enhancement pattern 30 s | 0.002 a | ||||
| 1: homogeneous | 18 (90.0%) | 18 (40.9%) | 9 (50.0%) | ||
| 2: mucosa only | 1 (5.0%) | 20 (45.5%) | 9 (50.0%) | ||
| 3: layered | 1 (5.0%) | 6 (13.6%) | 0 | ||
| Enhancement pattern 70 s | 0.004 a | ||||
| 1: homogeneous | 17 (85.0%) | 16 (36.4%) | 9 (50.0%) | ||
| 2: mucosa only | 2 (10.0%) | 22 (50.0%) | 9 (50.0%) | ||
| 3: layered | 1 (5.0%) | 6 (13.6%) | 0 | ||
| Enhancement pattern 7 min | 0.015 a | ||||
| 1: homogeneous | 18 (90.0%) | 22 (50.0%) | 14 (77.8%) | ||
| 2: mucosa only | 1 (5.0%) | 16 (36.4%) | 4 (22.2%) | ||
| 3: layered | 1 (5.0%) | 6 (13.6%) | 0 | ||
| Enhancement progression | 0.143 a | ||||
| 1: Stable over time | 13 (65.0%) | 17 (38.6%) | 9 (50.0%) | ||
| 2: Progression over time | 7 (35.0%) | 27 (61.4%) | 9 (50.30%) | ||
| Percentage of mucosa enhancement gain at 7 min vs 30 s, mean ± SD (range) | 58.64±61.38 (−11.15–169.89) |
56.95±52.01 (−3.03–200.57) |
65.16±56.78 (5.21–192.03) |
0.745 b | |
| Percentage of submucosa enhancement gain at 7 min vs 30 s, mean ± SD (range) | 63.71±56.82 (−3.13–169.89) |
84.60±60.66 (−10.93–237.47) |
84.77±63.89 (17.14–274.10) |
0.366 b | |
| Percentage of mucosa enhancement gain at 7 min vs 70 s, mean ± SD (range) | 8.99±24.91 (−17.62–86.18) |
6.95±16.63 (−16.66–73.11) |
5.33±9.48 (−8.42–26.80) |
0.957 b | |
| Percentage of submucosa enhancement gain at 7 min vs 70 s, mean ± SD (range) | 17.26±35.09 (−17.62–124.50) |
29.11±31.93 (−16.66–136.11) |
22.02±23.18 (−8.42–73.25) |
0.140 b | |
| Percentage of mucosa enhancement gain at 30 s vs precontrast, mean ± SD (range) | 85.74±60.05 (−1.92–244.60) |
109.99±77.08 (−5.22–294.02) |
88.48±70.86 (11.65–229.13) |
0.382 b | |
| Percentage of mucosa enhancement gain at 70 s vs precontrast, mean ± SD (range) | 153.10±59.41 (26.54–264.63) |
188.94±77.16 (33.78–358.21) |
175.58±82.71 (57.76–408.60) |
0.232 b | |
| Percentage of mucosa enhancement gain at 7 min vs precontrast, mean ± SD (range) | 169.10±60.23 (74.88–311.48) |
204.07±76.48 (35.24–342.81) |
187.94±77.01 (66.99–365.79) |
0.264 b | |
MT magnetization transfer, SD standard deviation, T2WI T2-weighted imaging
a
Chi-squared test;
b
Kruskal-Wallis test