Table 4.
Association between MRI parameters and histological fibrosis score
| Histological fibrosis score |
||||
|---|---|---|---|---|
| MRI parameters | None or Mild (n=13) | Moderate (n=42) | Severe (n=27) | P |
| MT ratio, mean ± SD (range) | 23.87±4.39 (19.10–33.01) |
35.41±5.54 (21.53–47.13) |
40.85±4.89 (32.31–50.79) |
<0.001 b |
| Wall thickness, mean ± SD (range) | 4.94±2.46 (2.50–10.30) |
9.42±2.72 (3.34–17.90) |
11.96±4.08 (6.86–22.80) |
<0.001 b |
| High signal intensity on T2WI | 2 (15.4%) | 35 (83.3%) | 21 (77.8%) | <0.001 a |
| Enhancement pattern 30 s | 0.091 a | |||
| 1: homogeneous | 11 (84.6%) | 18 (42.9%) | 16 (59.3%) | |
| 2: mucosa only | 2 (15.4%) | 20 (47.6%) | 8 (29.6%) | |
| 3: layered | 0 | 4 (9.5%) | 3 (11.1%) | |
| Enhancement pattern 70 s | 0.048 a | |||
| 1: homogeneous | 11 (84.6%) | 16 (38.1%) | 15 (55.6%) | |
| 2: mucosa only | 2 (15.4%) | 22 (52.4%) | 9 (33.3%) | |
| 3: layered | 0 | 4 (9.5%) | 3 (11.1%) | |
| Enhancement pattern 7 min | 0.580 a | |||
| 1: homogeneous | 11 (84.6%) | 26 (61.9%) | 17 (63.0%) | |
| 2: mucosa only | 2 (15.4%) | 12 (28.6%) | 7 (25.9%) | |
| 3: layered | 0 | 4 (9.5%) | 3 (11.1%) | |
| Enhancement progression | 0.192 a | |||
| 1: Stable over time | 9 (69.2%) | 17 (40.5%) | 13 (48.1%) | |
| 2: Progression over time | 4 (30.8%) | 25 (59.5%) | 14 (51.9%) | |
| Percentage of mucosa enhancement gain at 7 min vs 30 s, mean ± SD (range) | 60.03±53.94 (−3.13–169.89) |
59.24±56.14 (−11.15–192.03) |
58.61±55.27 (−3.03–200.57) |
0.962 b |
| Percentage of submucosa enhancement gain at 7 min vs 30 s, mean ± SD (range) | 63.63±52.98 (−3.13–169.89) |
88.89±67.38 (−10.93–274.10) |
72.66±50.97 (11.02–200.57) |
0.417 b |
| Percentage of mucosa enhancement gain at 7 min vs 70 s, mean ± SD (range) | 11.60±18.78 (−17.62–49.88) |
6.89±19.92 (−16.03–86.18) |
5.26±13.11 (−16.66–42.44) |
0.437 b |
| Percentage of submucosa enhancement gain at 7 min vs 70 s, mean ± SD (range) | 10.94±17.88 (−17.62–49.88) |
32.13±34.93 (−13.23–136.11) |
19.66±27.11 (−17.10–106.77) |
0.107 b |
| Percentage of mucosa enhancement gain at 30 s vs precontrast, mean ± SD (range) | 82.89±35.22 (20.10–161.48) |
90.50±65.86 (−1.92–244.60) |
121.04±89.42 (−5.22–294.02) |
0.473 b |
| Percentage of mucosa enhancement gain at 70 s vs precontrast, mean ± SD (range) | 153.11±49.40 (88.64–225.54) |
165.61±68.13 (26.54–314.14) |
207.03±87.77 (57.76–408.60) |
0.088 b |
| Percentage of mucosa enhancement gain at 7 min vs precontrast, mean ± SD (range) | 184.67±80.22 (74.88–311.48) |
176.72±59.68 (35.24–334.69) |
219.29±84.26 (66.99–365.79) |
0.069 b |
MT magnetization transfer, SD standard deviation, T2WI T2-weighted imaging
a
Chi-squared test;
b
Kruskal-Wallis test