Table 5.
Changes in blood eosinophils, total IgE levels, and eosinophils counts in nasal secretions.
| Item | Group | n | 0 Week | 4 Week | 8 Week | 12 Week | 16 Week |
|---|---|---|---|---|---|---|---|
| Nasal eosinophil count (score) | LH2171 | 93 | 0.4 ± 0.7 | 0.3 ± 0.7 # | 0.5 ± 0.9 | 0.4 ± 0.7 # | 0.3 ± 0.6 |
| Placebo | 94 | 0.5 ± 0.9 | 0.5 ± 0.8 | 0.6 ± 0.9 | 0.6 ± 0.9 | 0.5 ± 0.7 | |
| Blood eosinophil count (/μL) | LH2171 | 93 | 174.2 ± 141.9 | 176.8 ± 141.9 | 170.0 ± 118.2 | 183.1 ± 127.3 | 172.6 ± 140.2 |
| Placebo | 94 | 157.0 ± 105.8 | 164.7 ± 111.4 | 171.2 ± 127.4 ** | 180.0 ± 123.9 *** | 156.7 ± 132.9 | |
| Total IgE (UA/mL) | LH2171 | 93 | 212.5 ± 491.8 | 204.0 ± 419.3 | 164.1 ± 274.9 | 185.8 ± 363.2 | 207.2 ± 468.4 |
| Placebo | 94 | 268.7 ± 461.8 | 263.4 ± 481.4 | 285.6 ± 584.8 | 245.5 ± 484.4 * | 276.5 ± 614.2 |
Mean ± standard deviation. # p < 0.05 compared with the placebo group as per the Mann-Whitney U test. * p < 0.05, ** p < 0.01, *** p < 0.001 compared with the 0-week time-point, as per the paired t-test.