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. 2020 Nov 24;9(12):2536. doi: 10.3390/cells9122536
4E-BP1 eukaryotic translation initiation factor 4E-binding protein 1
AA arachidonic acid
ALA α-linolenic fatty acid
ALS amyotrophic lateral sclerosis
AMPK AMP-activated protein kinase
ApcMin/+ adenomatous polyposis coli, multiple intestinal neoplasia
ASCO American Society of Clinical Oncology
ATF4 activating transcription factor 4
BMI body mass index
BWL body weight loss
C26 Colon adenocarcinoma 26
CC cancer-induced cachexia
CRP C-reactive protein
DHA docosahexaenoic acid
EGCG epigallocatechin-3-gallate
EPA eicosapentaenoic acid
ESPEN European Society for Clinical Nutrition and Metabolism
Fbxo F-Box protein
FDA Food and Drug Administration
FFAs free fatty acids
FoxO3 forkhead box O3
GDF growth differentiation factor
GPR120 G-protein-coupled receptor 120
GPx glutathione peroxidase
H2O2 hydrogen peroxide
HMGB1 High Mobility Group Box 1
HHE 4-hydroxyhexenal
HIF-1α hypoxia-inducible factor 1 alpha
HNE hydroxy-4-nonenal
HO-1 heme oxygenase-1
IGF1 insulin-like growth factor 1
IL interleukin
IL-1ra IL-1 receptor antagonist
IRS1 insulin receptor substrate 1
LIF leukemia inhibitory factor
LLC Lewis lung carcinoma
MAC16 murine adenocarcinoma 16
MAPK mitogen-activated protein kinase
MCFA medium-chain fatty acid
MDA malondialdehyde
MENAC multimodality exercise/nutrition anti-inflammatory treatment for cachexia
mTOR mammalian target of rapamycin
MuRF1 muscle RING-finger protein-1
MUSA1 muscle ubiquitin ligase of SCF complex in atrophy 1
NAC N-acetyl cysteine
Nfe2l2 nuclear factor, erythroid derived 2, like 2
NF-kB nuclear factor kappa-light-chain-enhancer of activated B cells
NOS nitric oxide synthases
NOX NADPH oxidases
Nrf-2 nuclear factor erythroid 2-related factor 2
O2•− superoxide anion
OH hydroxyl free radical
OS oxidative stress
PBS phosphate-buffered saline
PGC1α peroxisome proliferator-activated receptor γ coactivator 1α
PI3K phosphatidylinositol-3-kinase
PIF proteolysis-inducing factor
PPARγ peroxisome proliferator-activated receptor gamma
PUFAs polyunsaturated fatty acids
ROS reactive oxygen species
S6K ribosomal protein S6 kinase beta 1
SCF Skp, Cullin, F-box
SIRT1 silent mating type information regulation 2 homolog 1
SOD superoxide dismutase
Sparc Secreted protein acidic and cysteine rich
STAT3 signal transducer and activator of transcription 3
sTNF-r soluble TNF receptor
Tak1 transforming growth factor-β activated kinase
TGFβ transforming growth factor beta
TLR4 Toll-like receptor 4
TMZ trimetazidine
TNFα tumor necrosis factor alpha
TORC1 mTOR complex
TRAF6 TNF receptor-associated factor 6
TWEAK TNF-related weak inducer of apoptosis
UCP uncoupling proteins
UPS ubiquitin proteasome system
WB-EMS whole-body electromyostimulation