Table 5.
Two-way analysis of treatment × time interaction in each cognitive domain scores of MoCA of active and placebo groups for female subjects.
| Sub-Category | Start-Up | Follow-Up | Treatment × Time Interaction | ||||
|---|---|---|---|---|---|---|---|
| Active a | Placebo a | Active a | Placebo a | Active a | Placebo a | p-Value b | |
| Executive | 4.6 ± 0.6 | 4.5 ± 0.9 | 4.6 ± 0.7 | 4.7 ± 0.5 | −0.1 ±0.9 | 0.3 ±0.8 | 0.2733 |
| Naming | 3.0 ± 0.0 | 2.9 ± 0.2 | 3.0 ± 0.0 | 3.0 ± 0.0 | 0.0 ± 0.0 | 0.1 ± 0.2 | 0.3364 |
| Attention | 5.3 ± 0.9 | 5.9 ± 0.4 | 5.5 ± 0.8 | 5.9 ± 0.5 | 0.2 ± 1.0 | 0.0 ± 0.6 | 0.5315 |
| Language | 1.3 ± 0.7 | 2.1 ± 0.9 | 2.0 ± 0.9 | 1.8 ± 0.7 | 0.7 ± 0.9 | −0.3 ± 0.9 | 0.0008 ** |
| Abstraction | 1.8 ± 0.4 | 2.0 ± 0.2 | 2.0 ± 0.0 | 2.0 ± 0.0 | 0.2 ± 0.4 | 0.1 ± 0.2 | 0.1411 |
| Delayed Recall | 3.2 ± 1.5 | 3.4 ± 1.5 | 3.7 ± 1.3 | 3.3 ± 1.4 | 0.6 ± 1.3 | −0.1 ± 1.6 | 0.1640 |
| Orientation | 5.1 ± 0.6 | 5.5 ± 0.5 | 5.5 ± 0.5 | 5.7 ± 0.5 | 0.4 ± 0.8 | 0.2 ± 0.8 | 0.5146 |
a Mean ± Standard Deviation; b Changes between start-up and follow-up. Multiple comparison correction was d by Bonferroni correction, and a p value of less than 0.0071 was defined as statistically significant. ** p < 0.0014.