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. 2020 Nov 24;10(12):997. doi: 10.3390/diagnostics10120997

Figure 1.

Figure 1

Shared genes and pathways between EAO, AOA and dystonia networks. Legend: (A) Venn diagram plot showing 472 common genes between EOA, AOA and dystonia. The gene networks of EOA—dystonia (n = 1004 (532 + 472)) reveal more overlap than the gene networks between AOA—dystonia (n = 500 (28 + 472)), suggesting that the gene networks of EOA is more similar to the dystonia network compared to the network of AOA—dystonia. (B) Top 10 of the most enriched pathways (top 10 ToppGene) of the common genes between EOA, AOA and dystonia. The most enriched pathways involved are involved in carboxylic acid—and organic acid metabolic process and fatty acid—and lipid metabolic process.