Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 27;10(12):1607. doi: 10.3390/biom10121607

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Collagen IV expression in facial human skin from female donors aged 8, 30, 60 and 74 years. Sections of frozen Tissue-Tek^® O.C.T.™-embedded skin biopsies were stained with the monoclonal anti-collagen IV antibody (Clone 94, Sigma-Aldrich, St. Quentin Fallavier, France) and the nuclei were stained with DAPI. Note the regular lessening of collagen IV labeling at the dermal-epidermal junction and the gradual disappearance of rete ridges with the increase in the age of donors. Epidermis, dermis, micro-vessels and the mean rete ridge length (n = 10) are indicated. Scale bar = 100 μm.