Table 1.

Examples of adaptative genes facilitating the survival of P. aeruginosa isolates (modified from Marvig-2015) [16].

Gene	Product/Function
aceE	Pyruvate dehydrogenase, quorum sensing
algU	Stress sigma factor regulating alginate production, biofilm formation
ampC	β-lactamase precursor, elongation, cell division
exoS	Effector protein, cytotoxic and antiphagocytic effects
fim	Fimbrial formation, motility, adhesion/attachment, receptor recognition
ftsI	Penicillin-binding protein, elongation, cell division
fusA1	Elongation factor G
gyrA	DNA gyrase subunit A, cell division
gyrB	DNA gyrase subunit B, cell division
lasR	Transcriptional regulator, quorum sensing
mexA	Multidrug efflux membrane fusion protein precursor
mexB	Multidrug efflux transporter
mexS p	Oxidoreductase involved in the regulation of multidrug efflux pump
mexY	Multidrug efflux transporter
mexZ	Transcriptional regulator of multidrug efflux pump
muc	Alginate production, biofilm formation
nalD	Transcriptional repressor of multidrug efflux pump
oprD	Outer membrane porin
phz	Phenazine synthesis, virulence factor regulator, quorum sensing
pvdA	Pioverdine, antibacterial effect, biofilm formation
pelA	Polysaccharide deacetylase
pil	Pili formation, motility, adhesion/attachment, receptor recognition
rhl	Elastase synthesis, quorum sensing
rsml	Rhamnolips synthesis, quorum sensing
rbdA	Protein with c-di-GMP cyclase and phosphodiesterase domain
yecS	L-cysteine transporter of ABC system