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(A) Minimum inhibitory concentration (MIC) and (B) minimum bactericidal concentration (MBC) synergism (syn) effects of silver nitrate (AgNO3) with hydrogen tetrachloroaurate trihydrate (HA, AuCl4•3H2O) combination against P. aeruginosa ATCC 27853 in Mueller–Hinton broth (MHB). Combination of Ag–Au (0.015 Ag + 0.03 Au) was the lowest fractional inhibitory concentration (FIC = 0.12) and the highest bactericidal synergism effect between all metal-based antibiotics combinations.
