Table 2.
MCS characteristics in patients with GCM.
| MCS Characteristics 1 | MCS Only (n = 16) | MCS + IS (n = 27) | Total (n = 43) | p-Value |
|---|---|---|---|---|
| MCS as initial treatment | 16/16 (100.0) | 16/19 (84.2) | 32/35 (91.4) | 0.73 |
| MCS after immunosuppression failed | 3/19 (15.8) | 3/35 (8.6) | ||
| Time from admission to MCS (days) | 14 (5, 39) | 8 (4, 17) | 9 (4, 22) | 0.38 |
| Intra-aortic balloon pump | 2/14 (14.3) | 4/22 (18.2) | 6/36 (16.7) | 1.00 |
| Impella | 0/16 (0.0) | 3/27 (11.1) | 3/43 (7.0) | 0.45 |
| VA ECMO | 2/13 (15.4) | 7/23 (30.4) | 9/36 (25.0) | 0.55 |
| Temporary LVAD prior to durable LVAD | 1/16 (6.2) | 1/27 (3.7) | 2/43 (4.7) | 1.00 |
| Temporary LVAD prior to durable BiVAD | 3/16 (18.8) | 2/27 (7.4) | 5/43 (11.6) | 0.53 |
| Any LVAD | 16/16 (100.0) | 27/27 (100.0) | 43/43 (100.0) | 0.09 |
| Bridge to transplant | 8/16 (50.0) | 18/27 (66.7) | 26/43 (60.5) | 0.45 |
| Bridge to recovery | 8/16 (50.0) | 9/27 (33.3) | 17/43 (39.5) | 0.45 |
| Time from admission to LVAD (days) | 14 (5, 39) | 8 (4, 17) | 9 (4, 22) | 0.38 |
| VAD support duration (days) | 20 (13, 98) | 48 (17, 137) | 39 (15, 137) | 0.54 |
| Durable LVAD | 4/16 (25.0) | 6/27 (22.2) | 10/43 (23.3) | 1.00 |
| HeartMate II LVAD | 3/16 (18.8) | 2/27 (7.4) | 5/43 (11.6) | 0.53 |
| Jarvik 2000 LVAD | 1/16 (6.2) | 1/27 (3.7) | 2/43 (4.7) | 1.00 |
| Unspecified durable LVAD | 0/16 (0.0) | 3/27 (11.1) | 3/43 (7.0) | 0.45 |
| Any biventricular support | 12/16 (75.0) | 21/27 (77.8) | 33/43 (76.7) | 1.00 |
| Durable BiVAD | 4/16 (25.0) | 7/27 (25.9) | 11/43 (25.5) | 0.95 |
| HeartWare BiVAD | 1/16 (6.2) | 3/27 (11.1) | 4/43 (9.3) | 1.00 |
| Total artificial heart | 0/16 (0.0) | 1/27 (3.7) | 1/43 (2.3) | 1.00 |
| Unspecified durable BiVAD | 3/16 (18.8) | 1/27 (3.7) | 4/43 (9.3) | 1.00 |
| Durable LVAD + Temporary RVAD | 1/16 (6.2) | 2/27 (7.4) | 3/43 (7.0) | 0.88 |
| HeartMate II LVAD + Centrimag RVAD | 1/16 (6.2) | 1/27 (3.7) | 2/43 (4.7) | 1.00 |
| HeartMate II LVAD + Abiomed RVAD | 0/16 (0.0) | 1/27 (3.7) | 1/43 (2.3) | 1.00 |
| Temporary Centrimag BiVAD | 4/16 (25.0) | 4/27 (14.8) | 8/43 (18.6) | 0.67 |
| Unspecified BiVAD | 3/16 (18.8) | 8/27 (29.6) | 11/43 (25.5) | 0.43 |
1 All values are reported as n (%) or median (IQR). Abbreviations—MCS: mechanical circulatory support, GCM: giant cell myocarditis, IS: immunosuppression, VA ECMO: veno-arterial extracorporeal membrane oxygenation, LVAD: left ventricular assist device, BiVAD: biventricular assist device, RVAD: right ventricular assist device.