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. 2020 Nov 28;11(12):1434. doi: 10.3390/genes11121434

Figure 6.

Figure 6

TYK2 expression in B-cell precursor acute lymphoblastic leukaemia (B-ALL) patients. qPCR was performed on cDNA obtained from 1 μg of RNA isolated from the bone marrow of B-ALL patients and peripheral blood mononuclear cells (PBMCs) of healthy donors. For each sample, data were standardised against GAPDH expression. (A) Total B-ALL patients compared to healthy donors. Red line shows the median in each group (1.009 vs. 0.7594). (B) Age-related TYK2 expression in B-ALL patients. Children under 18 years compared to adults (median: 0.9147 vs. 0.3609). Patients with TYK2 variants are highlighted with different colours. * p < 0.05, *** p ≤ 0.001.