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. 2020 Nov 28;12(12):3673. doi: 10.3390/nu12123673

Table 1.

Study schedule.

Events Pretrial Test Period of Time (Weeks) The End of the Examination
–2 0 4 8
Visit ● ● ● ● ●
Test-samples intake graphic file with name nutrients-12-03673-i001.jpg
Soy-isoflavone intake graphic file with name nutrients-12-03673-i002.jpg graphic file with name nutrients-12-03673-i002.jpg
Urine sampling ● ●
Feces sampling ● ● ●
CAS ● ● ●
Measurement of skin ● ● ●
Questionnaire of skin ● ●
Blood sampling ● ●
Medical interview ● ● ● ● ●
Diary graphic file with name nutrients-12-03673-i003.jpg

Subjects were selected according to the pretrial test, followed by a two-week pre-intake period and an eight-week treatment period. Each period of soy isoflavone ingestion was three days. CAS: Constipation assessment scale. The arrow means to do it daily in the indicated period.