Table 3.
Comparison of fecal microbiota between the YM and placebo group.
| Genus | Groups | Relative Abundance (%) | p-Value | ||
|---|---|---|---|---|---|
| Baseline | 4 Weeks | 8 Weeks | |||
| Bifidobacterium | YM | 9.1 ± 1.4 | 6.7 ± 1.1 | 6.6 ± 1.0 | 0.062 |
| Placebo | 6.2 ± 0.8 | 4.2 ± 0.6 | 5.1 ± 0.9 | ||
| Bacteroides | YM | 20.1 ± 1.9 | 27.7 ± 2.5 | 26.8 ± 2.1 | 0.076 |
| Placebo | 17.8 ± 1.8 | 21.8 ± 1.8 | 22.9 ± 1.9 | ||
| Parabacteroides | YM | 1.4 ± 0.3 | 2.0 ± 0.5 | 2.3 ± 0.4 | 0.064 |
| Placebo | 1.2 ± 0.2 | 1.3 ± 0.2 | 1.3 ± 0.1 | ||
| Rikenellaceae;g | YM | 1.4 ± 0.2 | 1.7 ± 0.4 | 2.0 ± 0.4 | 0.392 |
| Placebo | 2.1 ± 0.5 | 2.0 ± 0.3 | 2.2 ± 0.4 | ||
| Clostridiales;f;g * | YM | 0.8 ± 0.2 | 0.4 ± 0.1 | 0.9 ± 0.3 | 0.018 |
| Placebo | 1.9 ± 0.5 | 1.9 ± 0.5 | 2.5 ± 0.6 | ||
| Lachnospiraceae;g | YM | 4.3 ± 0.6 | 4.7 ± 0.6 | 4.6 ± 0.6 | 0.693 |
| Placebo | 4.7 ± 0.4 | 4.9 ± 0.4 | 4.7 ± 0.4 | ||
| Blautia | YM | 11.8 ± 1.4 | 8.7 ± 1.0 | 8.0 ± 1.2 | 0.942 |
| Placebo | 11.2 ± 1.2 | 8.3 ± 0.9 | 8.7 ± 0.9 | ||
| Coprococcus | YM | 5.6 ± 0.8 | 4.6 ± 0.6 | 4.6 ± 0.7 | 0.082 |
| Placebo | 7.2 ± 0.8 | 6.0 ± 0.7 | 5.9 ± 0.6 | ||
| Roseburia | YM | 4.0 ± 0.8 | 3.0 ± 0.5 | 3.1 ± 0.5 | 0.343 |
| Placebo | 4.3 ± 0.7 | 3.7 ± 0.6 | 3.9 ± 0.6 | ||
| Lachnospiraceae;g[Ruminococcus] | YM | 4.0 ± 0.8 | 2.8 ± 0.4 | 2.4 ± 0.3 | 0.340 |
| Placebo | 2.5 ± 0.5 | 2.6 ± 0.3 | 2.7 ± 0.4 | ||
| Ruminococcaceae;g ** | YM | 0.8 ± 0.2 | 0.7 ± 0.2 | 0.7 ± 0.2 | 0.008 |
| Placebo | 1.6 ± 0.4 | 2.1 ± 0.4 | 1.9 ± 0.4 | ||
| Faecalibacterium | YM | 14.5 ± 1.4 | 14.1 ± 1.4 | 14.1 ± 1.3 | 0.844 |
| Placebo | 14.6 ± 1.2 | 15.8 ± 1.1 | 13.2 ± 1.0 | ||
| Oscillospira | YM | 2.1 ± 0.3 | 1.9 ± 0.2 | 2.4 ± 0.3 | 0.424 |
| Placebo | 2.2 ± 0.2 | 2.4 ± 0.2 | 2.4 ± 0.2 | ||
| Ruminococcus * | YM | 2.3 ± 0.4 | 2.2 ± 0.3 | 2.5 ± 0.4 | 0.015 |
| Placebo | 3.2 ± 0.4 | 3.4 ± 0.4 | 3.8 ± 0.4 | ||
Data represent the mean ± SE. The p-values were calculated using repeated-measures ANOVA for the differences between groups without multiple comparison correction. Asterisks indicate overall significance between groups across time points (* p < 0.05, ** p < 0.01). Genera that showed significantly different abundance between groups at baseline were excluded.