Table 4.
Summary of the pre-clinical and clinical evidence supporting the impact of stress on magnesium homeostasis.
| Evidence of the Impact of Stress on Magnesium Homeostasis | |||
|---|---|---|---|
| Population Tested | Stress Stimulus | Impact on Magnesium | |
| Pre-clinical | Cats (N = 30) |
Withdrawal of blood; infusion of catecholamines; potassium poisoning | ↑Blood Mg [122] |
| Guinea pigs (41) | Noise | ↑Serum Mg, ↓Erythrocytes Mg [123] | |
| Rats (88) | Noise | ↑Serum Mg, ↓Erythrocytes Mg [124] | |
| Rats | Noise | ↓Serum Mg, ↓Erythrocytes Mg | |
| Dogs | Physical exercise, temperature | ↓Serum Mg [126] | |
| Rats | Ethanol/Restraint stress | ↓Serum Mg [127] | |
| Rats | Cold | ↓Tissue content of Mg [129] | |
| Sheep | Dietary Mg restriction, cold | ↓Plasma Mg [129] | |
| Clinical | Adults (N = 8) | Adrenaline infusion | ↓Plasma Mg [130] |
| Young adults (N = 35) | Chronic or sub-chronic psychological stress | ↓Plasma Mg [43] | |
| Healthy men (N = 16) | Chronic sleep deprivation | ↓Erythrocyte Mg [131] | |
| Young adults (N = 35) | University exams | ↑Urinary Mg [44] | |
| Young adults (N = 30) | University exams | ↓Erythrocyte Mg [132] | |
| Young adults (N = 25) | Noise | ↑Urinary Mg ↑Serum Mg [133] | |
| Healthy men (56) | Noise | ↑Serum Mg, ↓Erythrocytes Mg; ↑Urinary Mg [134] | |
| Healthy men | Short- and long-term physical exercise | ↑Plasma Mg [135] | |
Mg, magnesium; ↑, increase; ↓, decrease.