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. 2020 Nov 30;12(12):1167. doi: 10.3390/pharmaceutics12121167

Table 2.

Pharmacokinetic parameters of diazepam following various routes of administration [31,32,33].

Route of Administration Onset of Action (min) Peak Plasma Levels (min) Bioavailability
Oral 15–60 30–90 100%
IM 15–30 30–60 60%
Rectal 5–10 10–45 80–90%
Intranasal <5 >60 97%