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. 2020 Nov 28;9(12):1199. doi: 10.3390/antiox9121199

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Mycophenolate (MMF) improved the T cell profile of mesenteric lymph nodes (MLNs) in deoxycorticosterone acetate (DOCA)-salt rats. mRNA levels of cluster of differentiation (CD)3 (A), forkhead box P3 (FoxP3), and retinoid-related orphan receptor-γ (RORγ) (B) in MLNs. (C) Concentration of interleukin (IL)-17a and IL-10 was measured by ELISA in lymphocyte-conditioned medium obtained with MLNs from all experimental groups. Values are expressed as mean ± SEM (n = 7–9). * p < 0.05 and ** p < 0.01 compared with control (CTR) group. # p < 0.05 and ## p < 0.01 are significant differences compared with the untreated DOCA-salt group.