Table 3.
Association of the combined DDAH1 haplotype with outcome parameters.
| DDAH1 Haplotype | Relative Risk | 95% CI | p |
|---|---|---|---|
| (3× homozygous major versus 0× homozygous minor) | |||
| DCI | 1.103 | 0.925–1.315 | 0.273 |
| Vasospasm | 1.483 | 1.013–2.170 | 0.039 |
| Death | 1.000 | 0.898–1.113 | 1.000 |
| GOS < 4 at discharge | 1.364 | 1.105–1.683 | 0.003 |
| GOS < 4 after 3 months | 1.475 | 1.231–1.766 | <0.0001 |
| (3× homozygous major versus ≥ 1× homozygous minor) | |||
| DCI | 1.316 | 1.072–1.614 | 0.011 |
| Vasospasm | 0.983 | 0.774–1.247 | 1.000 |
| Death | 0.929 | 0.460–1.874 | 1.000 |
| GOS < 4 at discharge | 2.273 | 1.681–3.072 | <0.0001 |
| GOS < 4 after 3 months | 1.299 | 1.110–1.519 | 0.001 |
Details of the haplotype construction are given in Appendix A. Abbreviations: DCI, delayed cerebral ischemia; GOS, Glasgow outcome scale. p values presented were calculated by Chi2 test; significant p values are printed in bold type. Abbreviation: 95% CI, 95% confidence interval.