Table 2.

Alteration incidences of the driver genes.

Genes	Incidence	Reported Incidence	p-Value
EGFR	24.0% (187/780)	26.0% (1491/5738) [5]	p = 0.2282
Exon 19 deletion	55.1% (103/187)	47.1% (702/1491) [5]	p = 0.0391 †
Exon 21 L858R	31.0% (58/187)	37.3% (556/1491) [5]	p = 0. 0931
Exon 20 S768I	1.6% (3/187)	3.1% (12/382) [7]	p = 0.2824
T790M	0.5% (4/780)	1.4% (85/5738) [5]	p = 0.0268 †
Others	10.2% (19/187)	N/A	N/A
KRAS	18.7% (77/411)	14.0% (190/1355) [5]	p = 0.0195 †
ALK	3.9% (28/710)	4.2–10.5% [8]	N/A
ROS1	2.2% (7/322)	0.7–3.4% [15]	N/A
RET	2.1% (4/190)	1.0–3.0% [16]	N/A
MET (Amplification)	10.2% (18/172)	2–20% [2,16,17,18]	N/A
BRAF	4.3% (4/94)	1–5% [19]	N/A
ERBB2	5.8% (4/69)	2–5% [20]	N/A

† p < 0.05.