Table 2.
Reducers | Non-Reducers | |||||
---|---|---|---|---|---|---|
Time 0 Mean ± SD | Time 1 Mean ± SD | Time 2 Mean ± SD | Time 0 Mean ± SD |
Time 1 Mean ± SD |
Time 2 Mean ± SD | |
Weight kg | 72.64 ± 15.17 | 71.29 ± 14.55 [*] | 71.14 ± 14.29 | 73.79 ± 12.69 | 71.79 ± 11.97 [*] | 71.50 ± 11.87 |
BMI kg/m2 | 26.28 ± 5.31 | 25.78 ± 5.01 [*] | 25.72 ± 4.74 | 26.09 ± 3.67 | 25.39 ± 3.53 [*] | 25.30 ± 3.59 |
SBP mmHg |
134.3 ± 16.10 | 126.2 ± 10.94 [*] | 125.3 ± 10.69 | 134.2 ± 16.67 | 123.7 ± 8.17 [§] | 124.5 ± 9.95 |
DBP mmHg |
80.84 ± 12.23 | 75.88 ± 8.99 [*] | 74.97 ± 7.67 | 81.55 ± 11.18 | 74.71 ± 7.11 [*] | 75.21 ± 7.64 |
LVMI g/m2 |
97.09 ± 20.42 | -------------- | 86.38 ± 18.17 *[§] | 97.31 ± 18.91 | ------------ | 103.1 ± 21.06 *[§] |
UNaV mEq/24 h |
161.0 ± 42.22 | 113.6 ± 32.39 [§] | 97.3 ± 23.01 *[§] | 158.2 ± 48.66 | 106.8 ± 36.32 [§] | 152.6 ± 49.96 *[§] |
UKV mEq/24 h | 59.74 ± 24.50 | 54.81 ± 15.17 | 61.53 ± 15.91 | 63.39 ± 31.30 | 60.16 ± 28.82 | 60.92 ± 19.38 |
DDD | 1.72 ± 0.83 | 1.31 ± 0.74 [§] | 1.24 ± 0.70 | 1.83 ± 1.02 | 1.31 ± 0.72 [§] | 1.46 ± 0.75 |
Reducers n = 76 (Females/Males: 43/33), Age 65.00 ± 12.83; Non-Reducers n = 62 (Females/Males 35/27), Age 64.10 ± 11.91. Statistics: Between-group analysis: 1-way ANOVA, Kruskal-Wallis followed by Dunn’s multiple comparison test; * p < 0.05; § p< 0.001. Inside-group analysis: ANOVA followed by Newman Keuls multiple comparison test, or two-tailed Student’s t test; [*] p < 0.05 and [§] p < 0.001 vs. the respective previous time. BMI: body mass index; BP: blood pressure; DDD: defined daily dose; DBP: diastolic; LVMI: left ventricular mass index; SBP: systolic; UKV: 24-h urinary potassium (excretion); UNaV: 24-h urinary sodium (excretion). No sex-specific differences were found between groups (ANOVA, Kruskal-Wallis followed by Dunn’s multiple comparison test; p > 0.05).