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. 2020 Dec 2;12(12):3601. doi: 10.3390/cancers12123601
aa Amino acids
Akt/AKT Serine-threonine Protein Kinase (PKB, now called AKT1)
ANG-1, -2 Angiopoietin-1, -2
APC Adenomatous Polyposis Coli
(b)FGF (basic) Fibroblast Growth Factor
Bcl-2 B-cell lymphoma protein
BCL9 B cell CLL/lymphoma 9 protein
CDX Caudal Type Homeobox-2 Protein
CD44, 184 Cluster of Differentiation 44, 184
COX-2 Cyclooxygenase-2
CRC Colorectal Cancer
CXCL8 C-X-C motif ligand 8 (chemokine)
CXCR4 C-X-C chemokine receptor type 4
DKK-1, -4 Dickkopf-related protein 1;-4
ECs Endothelial Cells
ECM Extracellular Matrix
EMT Epithelial-Mesenchymal Transition
ERK1/2 Extracellular Signal-regulated Kinase ½
FAK Focal Adhesion Kinase
FOXQ1 Forkhead Box Q1 Protein
FRAT1 Frequently Rearranged in Advanced T-cell Lymphoma 1 Protein
FRPs Fzd-related Proteins
Fzd Frizzleds proteins, a family of G protein-coupled receptor proteins
GDF-15 Growth Differentiation Factor 15
GSK3β Glycogen Synthase Kinase 3 β
HIF-1α Hypoxia-inducible Factor 1 α
HUVECs Human Umbilical Vein ECs
IL Interleukin
KRAS Kirsten Rat Sarcoma Virus, proto-oncogene
LEF Lymphoid Enhancer Factor
MAPK A Mitogen-activated Protein Kinase
MMP-2, -9 Matrix Metalloproteinase 2, 9
MVD Microvessel Density
PI3K Phosphatidylinositol 3’ Kinase
PKA, B (AKT), C α Protein Kinase A, B (AKT), C α
PKG Type 1 cyclic Guanosine Monophosphate (cGMP)-dependent Protein Kinase
PLCγ1 Phospholipase C γ1
p-LPR6 Phosphorylated Lipoprotein-related Protein 6
ROS Reactive Oxygen Species
RAR Retinoic Acid Receptor
RORα RAR-related Orphan Receptor α;
RYK Related to Receptor Tyrosine Kinase protein
SALL4 Zink Finger Transcription Factor Spalt (Sall)-like Protein 4
SFRP2 Secreted Frizzled-related Protein 2
SMAD4 SMAD family member 4, Mothers Against Decapentaplegic Homolog 4
SMAR1 Scaffold/Matrix Attachment Region Binding Protein 1
STAT3 Signal Transducer and Activator of Transcription Protein Activator of Transcription 3
Tan IIA, TSA Tanshinone IIA
TCF T cell Factor, Transcription Factor
TCF7L2 Transcription Factor 7-like 2
TGF-β Tumor Growth Factor beta
TGM2 Tissue Transglutaminase 2
TIPE2 (TNFAIP8L2) TNFα-induced protein 8 like 2
TNF-α Tumor Necrosis Factor α
TNM T—tumor; N—lymph nodes; M—metastasis
TOPFlash TCF Reporter Plasmid
TP53 Tumor Protein 53
3’UTR 3’ Untranslated Region
VEGF Vascular Endothelial Growth Factor
VEGF (R) Vascular Endothelial Growth Factor (Receptor)