Table 4.
Probable biological activities of steroids derived from soft coral species estimated by PASS.
| No. | Antitumor and Related Activity, (Pa) * | Lipid Metabolism Regulators, (Pa) * | Additional biological activity, (Pa) * |
|---|---|---|---|
| 59 | Antineoplastic (0.886) Apoptosis agonist (0.648) |
Anti-hypercholesterolemic (0.819) Cholesterol synthesis inhibitor (0.570) |
Respiratory analeptic (0.888) Immunomodulator (HIV) (0.850) |
| 60 | Antineoplastic (0.843) Apoptosis agonist (0.780) Dementia treatment (0.528) |
Neuroprotector (0.611) Nootropic (0.587) Hypolipemic (0.536) |
Respiratory analeptic (0.835) |
| 61 | Antineoplastic (0.892) Apoptosis agonist (0.639) |
Anti-inflammatory (0.599) |
|
| 62 | Antineoplastic (skin cancer) (0.650) Antineoplastic (0.650) |
Anti-inflammatory (0.608) Immunomodulator (HIV) (0.568) |
|
| 63 | Antineoplastic (0.788) Apoptosis agonist (0.628) |
Hypolipemic (0.738) Cholesterol synthesis inhibitor (0.660) |
Antifungal (0.699) Anti-inflammatory (0.623) |
| 64 | Antineoplastic (0.824) Apoptosis agonist (0.634) |
Hypolipemic (0.707) Cholesterol synthesis inhibitor (0.533) |
Antifungal (0.777) |
| 65 | Antineoplastic (0.841) Proliferative diseases treatment (0.732) Apoptosis agonist (0.713) |
Anti-hypercholesterolemic (0.848) Hypolipemic (0.762) Cholesterol synthesis inhibitor (0.615) |
Respiratory analeptic (0.947) Immunosuppressant (0.834) |
| 66 | Antineoplastic (0.761) Proliferative diseases treatment (0.575) |
Anti-hypercholesterolemic (0.824) Atherosclerosis treatment (0.636) |
Respiratory analeptic (0.833) |
| 67 | Chemopreventive (0.882) Antineoplastic (0.830) Proliferative diseases treatment (0.738) |
Anti-hypercholesterolemic (0.884) Atherosclerosis treatment (0.679) |
Anti-inflammatory (0.860) Respiratory analeptic (0.848) |
| 68 | Antineoplastic (0.744) | Anti-inflammatory (0.691) | |
| 69 | Antineoplastic (0.875) Proliferative diseases treatment (0.856) |
Anti-hypercholesterolemic (0.918) Atherosclerosis treatment (0.618) |
Anti-inflammatory (0.903) Nootropic (0.654) |
| 70 | Antineoplastic (0.822) Prostate disorders treatment (0.796) |
Anti-hypercholesterolemic (0.634) | Erythropoiesis stimulant (0.858) Immunomodulator (HIV) (0.858) |
| 71 | Apoptosis agonist (0.964) Chemopreventive (0.906) Antineoplastic (0.854) |
Atherosclerosis treatment (0.865) Lipoprotein disorders treatment (0.761) Anti-hypercholesterolemic (0.694) |
Antiprotozoal (Plasmodium) (0.876) Respiratory analeptic (0.766) |
| 72 | Apoptosis agonist (0.982) Chemopreventive (0.945) Antineoplastic (0.920) Antiparkinsonian, rigidity relieving (0.730) |
Atherosclerosis treatment (0.909) Hypolipemic (0.831) Lipoprotein disorders treatment (0.816) Anti-hypercholesterolemic (0.799) |
Antiprotozoal (Plasmodium) (0.845) |
| 73 | Apoptosis agonist (0.970) Chemopreventive (0.929) Antineoplastic (0.883) Antiparkinsonian, rigidity relieving (0.614) |
Atherosclerosis treatment (0.904) Anti-hypercholesterolemic (0.856) Hypolipemic (0.838) Lipoprotein disorders treatment (0.733) |
Antiprotozoal (Plasmodium) (0.828) |
| 74 | Antineoplastic (0.891) Proliferative diseases treatment (0.600) |
Hypolipemic (0.683) | Anti-inflammatory (0.816) Antiprotozoal (Plasmodium) (0.719) |
| 75 | Antineoplastic (0.932) Proliferative diseases treatment (0.611) |
Anti-hypercholesterolemic (0.612) Autoimmune disorders treatment (0.587) |
Anti-inflammatory (0.886) |
| 76 | Antineoplastic (0.933) Proliferative diseases treatment (0.623) |
Anti-inflammatory (0.902) Respiratory analeptic (0.823) |
|
| 77 | Antineoplastic (0.905) Chemopreventive (0.617) |
Autoimmune disorders treatment (0.640) | Anti-inflammatory (0.863) Antiprotozoal (Plasmodium) (0.653) |
| 78 | Apoptosis agonist (0.854) Antineoplastic (0.787) |
Anti-hypercholesterolemic (0.769) Atherosclerosis treatment (0.635) |
Respiratory analeptic (0.941) |
| 79 | Antineoplastic (0.887) Apoptosis agonist (0.880) Chemopreventive (0.605) |
Anti-hypercholesterolemic (0.808) Hypolipemic (0.787) Atherosclerosis treatment (0.689) |
Anti-inflammatory (0.682) |
| 80 | Antineoplastic (0.799) Apoptosis agonist (0.701) |
Atherosclerosis treatment (0.611) Cholesterol synthesis inhibitor (0.589) |
Antifungal (0.751) Antithrombotic (0.558) |
| 81 | Antineoplastic (0.877) Apoptosis agonist (0.838) |
Anti-hypercholesterolemic (0.638) Cholesterol synthesis inhibitor (0.628) |
Respiratory analeptic (0.945) |
| 82 | Antineoplastic (0.857) | Antifungal (0.786) | |
| 83 | Antineoplastic (0.753) Alzheimer’s disease treatment (0.674) |
Anti-inflammatory (0.733) Immunosuppressant (0.723) |
|
| 84 | Antineoplastic (0.852) Apoptosis agonist (0.760) |
Respiratory analeptic (0.871) Immunosuppressant (0.781) |
* Only activities with Pa > 0.5 are shown.