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. 2020 Dec 2;18(12):613. doi: 10.3390/md18120613

Table 9.

Probable biological activities of steroids derived from soft coral species estimated by PASS.

No. Antitumor and Related Activity, (Pa) * Lipid Metabolism Regulators, (Pa) * Additional Biological Activity, (Pa) *
157 Antineoplastic (0.749) Anti-hypercholesterolemic (0.825) Anti-inflammatory (0.881)
158 Antineoplastic (0.701)
Prostate disorders treatment (0.629)
Anti-hypercholesterolemic (0.929)
Hypolipemic (0.645)
Anti-seborrheic (0.868)
Radioprotector (0.801)
159 Apoptosis agonist (0.791)
Antineoplastic (0.787)
Hypolipemic (0.680)
Anti-psoriatic (0.795)
Immunosuppressant (0.726)
160 Antineoplastic (0.913)
Apoptosis agonist (0.862)
Proliferative diseases treatment (0.687)
Atherosclerosis treatment (0.628)
Anti-hypercholesterolemic (0.587)
Anti-eczematic (0.844)
Anti-psoriatic (0.820)
161 Antineoplastic (0.860)
Apoptosis agonist (0.851)
Proliferative diseases treatment (0.700)
Anti-hypercholesterolemic (0.789)
Atherosclerosis treatment (0.724)
Cholesterol synthesis inhibitor (0.617)
Anti-osteoporotic (0.913)
Nootropic (0.870)
162 Antineoplastic (0.872)
Apoptosis agonist (0.811)
Proliferative diseases treatment (0.786)
Anti-hypercholesterolemic (0.943)
Hypolipemic (0.730)
Atherosclerosis treatment (0.648)
Anesthetic general (0.917)
Respiratory analeptic (0.869)
Nootropic (0.698)
163 Antineoplastic (0.937)
Apoptosis agonist (0.906)
Proliferative diseases treatment (0.886)
Antiparkinsonian, rigidity relieving (0.729)
Multiple sclerosis treatment (0.565)
Anti-eczematic (0.973)
Anti-psoriatic (0.963)
Anti-osteoporotic (0.961)
Hyperparathyroidism treatment (0.842)
Hypercalcemia treatment (0.509)
164 Antineoplastic (0.706)
Proliferative diseases treatment (0.608)
Anti-hypercholesterolemic (0.882)
Atherosclerosis treatment (0.723)
Cholesterol synthesis inhibitor (0.632)
Hepatic disorders treatment (0.824)
Anti-osteoporotic (0.665)
165 Antineoplastic (0.750)
Anti-hypercholesterolemic (0.791)
Atherosclerosis treatment (0.700)
Acute neurologic disorders treatment (0.635)
Hepatic disorders treatment (0.816)
Anesthetic general (0.774)
Anti-osteoporotic (0.663)
166 Antineoplastic (0.694)
Apoptosis agonist (0.578)
Proliferative diseases treatment (0.542)
Anti-hypercholesterolemic (0.852)
Hypolipemic (0.788)
Atherosclerosis treatment (0.744)
Anti-eczematic (0.870)
Hepatic disorders treatment (0.817)
Anti-osteoporotic (0.678)
167 Antineoplastic (0.789)
Apoptosis agonist (0.726)
Proliferative diseases treatment (0.608)
Anti-hypercholesterolemic (0.891)
Atherosclerosis treatment (0.630)
Acute neurologic disorders treatment (0.560)
Anti-eczematic (0.894)
Anti-psoriatic (0.777)
Anti-osteoporotic (0.736)
168 Proliferative diseases treatment (0.947)
Dementia treatment (0.657)
Neuroprotector (0.981)
Anti-hypercholesterolemic (0.971)
Hypolipemic (0.778)
Respiratory analeptic (0.987)
Hepatoprotectant (0.945)
Anesthetic general (0.903)
169 Proliferative diseases treatment (0.920)
Antineoplastic (0.841)
Dementia treatment (0.661)
Anti-hypercholesterolemic (0.962)
Neuroprotector (0.952)
Acute neurologic disorders treatment (0.783)
Respiratory analeptic (0.991)
Anesthetic general (0.922)
Spasmolytic (0.719)
170 Antineoplastic (0.793)
Proliferative diseases treatment (0.605)
Anesthetic general (0.815)
Cardiotonic (0.770)
171 Antineoplastic (0.872)
Alzheimer’s disease treatment (0.634)
Proliferative diseases treatment (0.625)
Neuroprotector (0.732)
Hypolipemic (0.592)
Acute neurologic disorders treatment (0.557)
Anti-inflammatory (0.923)
Nootropic (0.672)
172 Antineoplastic (0.871)
Alzheimer’s disease treatment (0.681)
Dementia treatment (0.576)
Neuroprotector (0.762)
Anti-hypercholesterolemic (0.633)
Neurodegenerative diseases treatment (0.618)
Respiratory analeptic (0.894)
Anesthetic general (0.890)
173 Proliferative diseases treatment (0.922)
Antineoplastic (0.842)
Anti-hypercholesterolemic (0.859)
Neuroprotector (0.706)
Respiratory analeptic (0.962)
Anti-ischemic, cerebral (0.864)
174 Proliferative diseases treatment (0.935)
Antineoplastic (0.837)
Dementia treatment (0.616)
Anti-hypercholesterolemic (0.927)
Neuroprotector (0.773)
Hypolipemic (0.584)
Anti-ischemic, cerebral (0.944)
Respiratory analeptic (0.940)
Antithrombotic (0.720)
175 Antineoplastic (0.793)
Anti-hypercholesterolemic (0.954)
Neuroprotector (0.754)
Hypolipemic (0.704)
Respiratory analeptic (0.979)
Anesthetic general (0.927)
Anti-ischemic, cerebral (0.679)
176 Antineoplastic (0.893)
Proliferative diseases treatment (0.768)
Anti-hypercholesterolemic (0.899)
Atherosclerosis treatment (0.754)
Respiratory analeptic (0.979)
Immunomodulator (HIV) (0.912)
177 Antineoplastic (0.812)
Dementia treatment (0.505)
Neuroprotector (0.938)
Anti-hypercholesterolemic (0.912)
Atherosclerosis treatment (0.548)
Respiratory analeptic (0.984)
Immunomodulator (HIV) (0.933)
Anesthetic general (0.917)

* Only activities with Pa > 0.5 are shown.