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. 2020 Dec 2;12(12):1175. doi: 10.3390/pharmaceutics12121175

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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GastroPlus^® simulated (line) versus mean observed (markers) plasma concentration profiles following p.o. administration of furosemide. Mean observed values represent 40 mg immediate-release (IR) tablet profile I [43] and 40 mg IR tablet profile II [37].