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. 2020 Dec 2;12(12):3609. doi: 10.3390/cancers12123609

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Chemicals activated by NQO1 and NQO2. The structures of mitomycin C, 17-allylaminodemethoxygeldanamycin, deoxynyboquinone, β-lapachone and CB1954 (Tretazicar), which are bio-reductively activated by NQO1 and NQO2, are shown.