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. 2020 Dec 3;9(12):3924. doi: 10.3390/jcm9123924

Table 1.

Algorithm evaluation of LVDD [9].

Normal
EF (≥50%)
1. Average E/e’ > 14
2. Septal e’ velocity < 7 cm/s or lateral e’ velocity
< 10 cm/s
3. TR velocity max
> 2.8 m/s
4. LAVI > 34 mL/m2
1st criteria fulfilled Normal LVDD
2nd criteria fulfilled Indeterminate LVDD
3rd or 4th criteria fulfilled Abnormal LVDD
Depressed EF (<50%) E/A ≤ 0.8 + E ≤ 50 cm/s Grade I LVDD
E/A ≤ 0.8 + E > 50 cm/s
or 0.8 < E/A < 2
When possible assessment of 3 criteria:
1. Average E/e’ >14
2. TR velocity
>2.8 m/s
3. LAVI
> 34 mL/m2
2 of 3 or 3 of 3 Negative
When only 2 criteria are available 2 negative
1 positive and
1 negative
Indeterminate LVDD
1 negative Grade II LVDD
2 of 3 or 3 of 3 Positive
E/A ≥ 2 Grade III LVDD

LVDD, left ventricular diastolic dysfunction; EF, ejection fraction; E, peak early diastolic velocity; e’, early diastolic mitral annular tissue velocity; TR, tricuspid regurgitation; LAVI, left atrial volume index; A, peak late diastolic velocity; cm, centimeter; s, second; m, meter; ml, milliliter.