Figure 2.

Graphical depiction of the different subgroups of primary meningiomas with CNS invasion that were analyzed. The color represents the mode of assessment: histopathology (green and yellow), intraoperative (yellow and blue), combined histopathology and intraoperative (green, yellow and blue), double positive by histopathology and intraoperative (yellow), only positive by intraoperative assessment (blue). All subgroups were significant factors for tumor recurrence in the univariate analysis, but only the combined assessment (histopathology and intraoperative) turned out to be an independent significant prognostic factor in the multivariate analysis (asterisk (*): statistically significant result).