Table 2.
Multivariate analysis of the histopathologically and intraoperatively assessed CNS invasion (Cox proportional hazard).
| Variable | Histopathology | Intraoperative | ||
|---|---|---|---|---|
| Risk Ratio (95% CI) | p-Value (Prob > Chisq) | Risk Ratio (95% CI) | p-Value (Prob > Chisq) | |
| Male gender | 1.38 (1.05–1.82) | 0.0227 * | 1.33 (1.00–1.77) | 0.0474 * |
| Localization | ||||
| Spinal vs. skull base | 0.42 (0.17–1.02) | 0.0562 | 0.45 (0.18–1.10) | 0.0803 |
| Spinal vs. convexity/falx | 0.56 (0.22–1.38) | 0.2084 | 0.62 (0.24–1.54) | 0.3009 |
| Convexity/falx vs. skull base | 0.75 (0.56–0.99) | 0.0430 * | 0.73 (0.54–0.99) | 0.0411 * |
| Simpson grade </= 3 | 0.42 (0.32–0.55) | <0.0001 * | 0.40 (0.30–0.52) | <0.0001 * |
| WHO classification 2007 | ||||
| I vs. II | 0.40 (0.29–0.56) | <0.0001 * | 0.44 (0.32–0.60) | <0.0001 * |
| I vs. III | 0.19 (0.05–0.80) | 0.0239 * | 0.17 (0.04–0.73) | 0.0169 * |
| II vs. III | 0.48 (0.12–1.99) | 0.311 | 0.40 (0.10–1.66) | 0.2062 |
| CNS invasion by histopathological/intraoperative assessment | 1.11 (0.70–1.76) | 0.6551 | 1.34 (0.99–1.82) | 0.0613 |
Asterisk (*): statistically significant result.