Table 1.
Linear regression analysis between lipid level (fractional change), and GWG and WL. Only lipids which were found to be significantly associated with either GWG or WL are shown below (p threshold = 0.0017). Bonferroni correction is used to account for multiple testing.
| Lipid Species | Beta GWG | 95% Confidence | p | Beta WL | 95% Confidence | p |
|---|---|---|---|---|---|---|
| PC (42:6) | −0.011 | (−0.015, −0.007) | 8.9 × 10−8 | 0.009 | (0.001, 0.018) | 3.5 × 10−2 |
| SM (d17:1/24:1) | −0.011 | (−0.015, −0.007) | 5.6 × 10−7 | 0.013 | (0.007, 0.019) | 1.2 × 10−5 |
| PC (O-18:1_20:4) | −0.015 | (−0.022, −0.009) | 2.2 × 10−6 | 0.026 | (0.017, 0.036) | 3.4 × 10−7 |
| PC (O-20:0_20:4) | −0.018 | (−0.025, −0.01) | 6.2 × 10−6 | 0.006 | (0.001, 0.011) | 2.0 × 10−2 |
| PC (40:8) | −0.013 | (−0.019, −0.007) | 2.4 × 10−5 | 0.011 | (0.005, 0.016) | 2.4 × 10−4 |
| PC (16:0_20:4) | 0.009 | (0.005, 0.013) | 2.8 × 10−5 | −0.004 | (−0.007, 0) | 2.8 × 10−2 |
| PC (O-18:1_16:0) | −0.011 | (−0.016, −0.006) | 2.9 × 10−5 | 0.010 | (0.002, 0.017) | 9.7 × 10−3 |
| SM (d18:2/24:1) | −0.014 | (−0.021, −0.008) | 6.4 × 10−5 | 0.007 | (0.002, 0.012) | 6.4 × 10−3 |
| PC (O-24:2_20:4) | −0.009 | (−0.014, −0.005) | 1.2 × 10−4 | 0.006 | (0.002, 0.01) | 5.8 × 10−3 |
| PC (O-22:1_18:1) | −0.014 | (−0.021, −0.007) | 1.5 × 10−4 | 0.009 | (0.005, 0.014) | 9.8 × 10−5 |
| SM (d18:1/24:1) | −0.010 | (−0.016, −0.005) | 4.3 × 10−4 | 0.006 | (0.001, 0.011) | 1.4 × 10−2 |
| PC (O-16:0_22:4) | −0.012 | (−0.019, −0.005) | 9.0 × 10−4 | 0.003 | (−0.001, 0.007) | 1.6 × 10−1 |
| LPC (O-18:1) | −0.014 | (−0.022, −0.006) | 9.7 × 10−4 | 0.047 | (0.02, 0.074) | 9.0 × 10−4 |
| LPC (O-16:1) | −0.011 | (−0.017, −0.004) | 1.2 × 10−3 | 0.082 | (0.034, 0.13) | 9.4 × 10−4 |
| PC (O-24:1_20:4) | −0.008 | (−0.013, −0.003) | 1.2 × 10−3 | 0.007 | (0.003, 0.012) | 2.7 × 10−3 |
| PI (16:0_16:1) | 0.140 | (0.055, 0.226) | 1.5 × 10−3 | −0.016 | (−0.026, −0.006) | 1.3 × 10−3 |
| PC (16:0_22:5) | 0.022 | (0.009, 0.036) | 1.6 × 10−3 | −0.008 | (−0.014, −0.003) | 3.8 × 10−3 |
| SM (d18:2/14:0) | 0.009 | (0.002, 0.016) | 1.2 × 10−2 | −0.013 | (−0.019, −0.007) | 1.1 × 10−4 |
| LPC (O-16:0) | −0.009 | (−0.016, −0.002) | 1.4 × 10−2 | 0.064 | (0.03, 0.098) | 3.3 × 10−4 |
| PC (18:1_18:2) | 0.079 | (0.013, 0.145) | 2.0 × 10−2 | −0.014 | (−0.022, −0.006) | 7.1 × 10−4 |
| PC (16:1_18:2) | 0.013 | (0.002, 0.025) | 2.2 × 10−2 | −0.012 | (−0.017, −0.006) | 1.6 × 10−4 |
| PI (16:0_18:2) | 0.012 | (−0.004, 0.029) | 1.4 × 10−1 | −0.009 | (−0.014, −0.004) | 8.9 × 10−4 |
| LPS(O-18:0) | −0.005 | (−0.012, 0.002) | 1.8 × 10−1 | 0.156 | (0.082, 0.229) | 5.3 × 10−5 |
| DG (18:1_18:2) | −0.013 | (−0.041, 0.015) | 3.4 × 10−1 | −0.010 | (−0.017, −0.004) | 1.5 × 10−3 |
| PC (14:0_18:2) | 0.007 | (−0.017, 0.031) | 5.7 × 10−1 | −0.017 | (−0.025, −0.01) | 1.3 × 10−5 |
| PC (15:0_18:2) | 0.000 | (−0.009, 0.009) | 9.6 × 10−1 | −0.008 | (−0.012, −0.003) | 9.8 × 10−4 |