Skip to main content
. 2020 Dec 4;9(12):446. doi: 10.3390/biology9120446

Figure 5.

Figure 5

Human Epidermal growth factor Receptor 2 (HER2) expression level in SKOV-3 and SKOV-3.ip cells cultured in monolayer and 3D in vitro models. (A) The distributions of SKOV-3 cells (left plot) and SKOV-3.ip cells (right plot) according to fluorescence intensity detected after staining with HER2-specific antibodies (red—monolayer culture, blue—spheroids, green—collagen hydrogel); (B) HER2 expression level in monolayer and 3D models denoted as relative fluorescence values. mnlr, monolayer; sph, spheroids; clgn, collagen hydrogel. “*” indicates significant difference in RF level from monolayer culture (ANOVA, Holm–Sidak’s multiple comparisons test, p < 0.05).