Table 3.
Diagnostic performance of allergy tests in milk and egg allergy and anaphylaxis for total subjects.
| Diagnosis | Diagnostic Tool | AUC (95% CI) | Comparison of AUCs between (p-Value) | |||
|---|---|---|---|---|---|---|
| sIgE vs. BAT | BAT vs. Combined | sIgE vs. Combined | ||||
| Tested for milk allergy (n = 75) |
Milk allergy (n = 26) |
sIgE | 0.701 (0.602–0.800) | 0.373 | 0.157 | 0.029 * |
| BAT | 0.758 (0.655–0.860) | |||||
| Combined sIgE and BAT | 0.805 (0.707–0.904) | |||||
| Anaphylaxis (n = 5) |
sIgE | 0.790 (0.651–0.929) | 0.949 | 0.784 | 0.991 | |
| BAT | 0.797 (0.532–1.000) | |||||
| Combined sIgE and BAT | 0.791 (0.509–1.000) | |||||
| Tested for egg allergy (n = 85) |
Egg allergy (n = 42) |
sIgE | 0.777 (0.687–0.866) | 0.989 | 0.830 | 0.781 |
| BAT | 0.776 (0.687–0.865) | |||||
| Combined sIgE and BAT | 0.766 (0.681–0.852) | |||||
| Anaphylaxis (n = 6) |
sIgE | 0.624 (0.476–0.772) | 0.661 | 0.867 | 0.705 | |
| BAT | 0.577 (0.367–0.787) | |||||
| Combined sIgE and BAT | 0.561 (0.304–0.818) | |||||
sIgE, specific immunoglobulin E; BAT, basophil activation test; AUC, area under the receiver operating characteristic curve; CI, confidence interval; Combined, Combined sIgE and BAT. * p < 0.05 for comparison of AUCs using the Delong method.