Figure 3.

Serum lipid levels and hepatic enzyme activity. Administration of APH for 12 weeks produced significant serum total cholesterol and triglycerides-lowering effects (A,B). Serum ALT (alanine aminotransferase) (C) and AST (aspartate amino transferase) (D) levels were statistically lower in ApoE^–/– HFD + APH compared to the control group (p < 0.0001), suggesting minor damage of the hepatocytes. Data are presented as mean ± SD for n = 6 mice per group. Abbreviations: HFD high-fat diet, APH anchovy protein hydrolysates.