Figure 1.

Portraying the biology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), mode of virus transmission, non-vaccine prevention strategies, and potential vaccine candidates that have progressed to clinical trials. (A) Viral structure and infection by binding of S protein to host receptor ACE2, (B) the transmission pathways, (C) identification of areas for further studies facilitating vaccine development, (D) non-vaccine strategies to contain the spread of infection, (E) potential vaccine may act through the production of neutralizing antibodies and/or cytotoxic CD8+ T cells that destroy the infected cells, (F) vaccine platforms for creating anti-SARS-CoV-2 vaccines, (G) number of potential vaccines entered into clinical trials.