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. 2020 Dec 5;12(12):3658. doi: 10.3390/cancers12123658

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Relative biological effectiveness (RBE) versus LET/y_d results in the context of the PIDE database and the H460 data from the current study. The RBE was calculated at a surviving fraction level of 0.1 (RBE (0.1 SF)) for cells exposed to protons (blue circles), helium ions (red squares), or carbon ions (green triangles). The H460 results from the current study (solid shapes; black outline) and the data present in the PIDE database (open shapes) are plotted for visual comparison. LET is used for the PIDE data while y_d is used for the current H460 data.