Figure 4.

Severity grading based on the modified Kupperman menopausal index scores: (a) placebo and (b) CGA. Severity grading was assessed according to the following scores: 0–12 is I, 13–22 is II, 23–33 is III, 34–43 is IV, and 44–51 is V. I and II are considered as mild, III as moderate, and IV and V as severe. Comparisons between placebo vs. CGA were p = 0.906, p = 0.016, and p = 0.173 for weeks 0, 2, and 4, respectively, as assessed by a logistic regression model with a threshold score between 22 and 23. Numbers in parentheses indicate frequencies. CGA, chlorogenic acid.