Table 2.
General and echocardiographic characteristics of HCM subjects with (G+) or without (G−) definitive genetic results.
| Variable | G+ (n = 6) | G− (n = 39) | p |
|---|---|---|---|
| Age at inclusion, years | 34 ± 10.3 | 53 ± 14.7 | 0.04 |
| Sex: male, n (%) | 6 (100%) | 27 (69.2%) | 0.31 |
| Family history of HCM, n (%) | 2 (33.3%) | 5 (12.82%) | 0.06 |
| Family history of SCD, n (%) | 4 (66.7%) | 10 (25.6%) | 0.065 |
| ICD, n (%) | 1 (16.7%) | 6 (15.4%) | 0.68 |
| Atrial fibrillation, n (%) | 5 (83.33%) | 17 (43.6%) | 0.35 |
| Echocardiographic data | |||
| Maron classification, n (%) | |||
| 1 | 2 (33.3%) | 5 (17.9%) | 0.56 |
| 2 | 1 (16.7%) | 4 (10.3%) | |
| 3 | 3 (50%) | 29 (69.2%) | |
| 4 | 0 | 1 (2.6%) | |
| Presence of LVOTO, n (%) | 1 (16.7%) | 19 (48.7%) | 0.29 |
| LV maximal wall thickness, mm | 18.83 ± 7.28 | 20.97 ± 4.88 | 0.36 |
| LV mass, g | 262.4 ± 113.7 | 275.45 ± 96 | 0.53 |
| LVEDD, mm | 46.2 ± 9 | 39.9 ± 7.17 | 0.13 |
| LVESD, mm | 26 ± 7.29 | 24 ± 10.8 | 0.66 |
| LVEDV, ml | 106.85 ± 37.33 | 121.6 ± 44.22 | 0.43 |
| LVESV, ml | 50.96 ± 26.82 | 55.4 ± 21.3 | 0.64 |
| LVEF, (%) | 58.52 ± 19.9 | 56.6 ± 13.36 | 0.76 |
| LAD, mm | 39.8 ± 5.49 | 40.74 ± 7 | 0.77 |
| LAV, ml | 117.8 ± 68.18 | 83.19 ± 41.9 | 0.12 |
HCM hypertrophic cardiomyopathy; ICD internal cardiac defibrillator; LAD left atrium diameter; LAV left atrium volume; LV left ventricular; LVEDD left ventricular end-diastolic diameter; LVEDV left ventricular end-diastolic volume; LVEF left ventricular ejection fraction; LVESD left ventricular end-systolic diameter; LVESV left ventricular end-systolic volume; LVOTO left ventricular outflow tract obstruction; PW posterior wall; SCD sudden cardiac death.