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. 2020 Dec 21;12:13033–13042. doi: 10.2147/CMAR.S267357

Figure 3.

Figure 3

H19 can negatively regulate miR-138. (A) miR-138 and H19 had targeted binding sites. (B) miR-138-mimics could inhibit H19-3ʹUTR Wt luciferase activity, with no remarkable effect on H19-3ʹUTR Mut luciferase activity. (C) miR-138 rose in GCCs after si-H19 transfection. (D) miR-138 rose in GCCs after miR-138-mimics transfection. (E and F) Cell proliferation reduced after miR-138-mimics transfection. (G) Cells penetrating the membrane were relatively few after miR-138-mimics transfection. (H) The apoptotic rate rose after miR-138-mimics transfection.

Notes: *Indicates P<0.05 when compared with the miR-NC group. aIndicates P<0.05 when compared with the si-NC group.