Table 2. Laboratory indicators of COVID-19 patients in severe or non-severe groups.
| All patients (n=113) | Non-severe patients (n=60) | Severe patients (n=53) | P value | |
| Blood cell count, × 109 per L | ||||
| White blood cell | 6.76±3.30 | 5.92±2.46 | 7.75±3.87 | 0.007 |
| Neutrophil | 3.89 (2.67-7.00) | 3.39 (2.19-4.61) | 5.96 (3.33-9.80) | < 0.001 |
| Lymphocytes | 1.10±0.57 | 1.42±0.56 | 0.73±0.27 | < 0.001 |
| Monocytes | 0.46±0.21 | 0.53±0.20 | 0.38±0.19 | < 0.001 |
| Platelet count, × 109 per L | 226.71±85.51 | 242.68±86.50 | 207.68±81.15 | 0.110 |
| Red cell count, × 109 per L | 4.14±0.59 | 4.23±0.56 | 4.04±0.62 | 0.038 |
| Haemoglobin, g/L | 128.00 (120.00-137.75) | 130.50 (120.00-139.75) | 127.50 (11950-137.00) | 0.557 |
| Albumin, g/L | 37.86±5.96 | 40.29±5.74 | 34.86±4.76 | < 0.001 |
| CRP, mg/L | 35.80 (5.00-87.18) | 6.50 (2.50-38.70) | 88.60 (33.60-152.80) | < 0.001 |
| ALT, U/L | 24.00 (17.00-42.00) | 19.5 0(16.00-28.50) | 37.00 (21.00-51.00) | < 0.001 |
| TB, mmol/L | 12.00 (8.90-15.80) | 10.90 (8.20-14.30) | 13.30 (10.15-17.58) | 0.021 |
| Potassium, mmol/L | 4.08±0.65 | 4.13±0.54 | 4.03±0.77 | 0.456 |
| Sodium, mmol/L | 141.68±5.09 | 143.61±4.30 | 139.28±5.01 | < 0.001 |
| Calcium, mmol/L | 2.13 (2.03-2.22) | 2.18 (2.13-2.28) | 2.05 (1.95-2.12) | < 0.001 |
| Creatinine, μmol/L | 63.00 (53.00-74.00) | 63.00 (53.00-71.5) | 63.5 (52.50-63.50) | 0.979 |
| IL2, pg/L | 3.59 (3.17-3.98) | 3.56 (3.17-4.12) | 3.67 (3.17-3.98) | 0.793 |
| IL4, pg/L | 3.20±0.63 | 3.09±0.70 | 3.31±0.53 | 0.278 |
| IL6, pg/L | 10.20 (5.77-37.20) | 6.49 (4.34-11.94) | 16.38 (7.65-70.98) | < 0.001 |
| IL10, pg/L | 5.85 (4.64-7.60) | 5.30 (4.32-6.21) | 6.19 (5.24-12.16) | 0.007 |
| TNF-α, pg/L | 3.18 (2.68-5.35) | 3.01 (2.59-5.71) | 3.21 (2.75-5.59) | 0.607 |
| INF-γ, pg/L | 3.44 (3.01-5.24) | 3.42 (2.82-5.38) | 3.44 (3.11-4.29) | 0.808 |
| LDH, U/L | 313.22±153.57 | 230.29±81.35 | 416.42±160.25 | < 0.001 |
| cTnI, pg/mL | 0.006 (0.000-0.010) | 0.006 (0.000-0.006) | 0.007 (0.006-0.028) | < 0.001 |
| BNP, pg/mL | 144.50 (51.58-369.08) | 79.25 (21.51-165.23) | 276.05 (119.03-869.43) | < 0.001 |
| CK, U/L | 58.00 (40.00-103.00) | 51.50 (36.25-71.50) | 78.00 (51.50-153.50) | 0.002 |
| CKMB, U/L | 1.13 (0.64-1.72) | 0.96 (0.61-1.27) | 1.48 (0.90-2.82) | < 0.001 |
| D-dimer, mg/L | 0.81 (0.36-2.30) | 0.43 (0.26-1.14) | 2.19 (0.83-8.39) | < 0.001 |
| Procalcitonin, ng/mL | 0.43 (0.13-3.80) | 2.80 (0.12-4.03) | 0.30 (0.14-2.95) | 0.722 |
Data are median (IQR), mean±SEM. p values were calculated by Mann-Whitney U test or t test as appropriate. Abbreviation: CRP, C-reactive protein; ALT, alanine aminotransferase; TB, total bilirubin; LDH, lactate dehydrogenase; cTnI, cardiac troponin I;BNP, brain natriuretic peptide; CK, creatine kinase; CKMB, creatine kinase-MB.