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. 2020 Nov 23;12(23):23464–23477. doi: 10.18632/aging.104148

Table 3. Pulmonary ventilation and oxygen content of COVID-19 patients in severe or non-severe groups.

All patients (n=113) Non-severe patients (n=60) Severe patients (n=53) P value
Oxygenation
Nasal tube 91 (80.5%) 39 (65.0%0 52 (98.1%) < 0.001
Facial mask 49 (43.4%) 3 (5.0%) 46 (86.8%) < 0.001
HFNC 34 (30.1%) 2 (3.3%) 32 (60.4%) < 0.001
NIV 18 (15.9%) 0 (0.0%) 18 (34.0%) < 0.001
IMV 14 (12.4%) 0 (0.0%) 14 (26.4%) < 0.001
ECMO 2 (1.8%) 0 (0.0%) 2 (3.8%) 0.218
Arterial blood gas analysis
PH 7.41±0.08 7.41±0.07 7.41±0.08 0.899
PO2, mmHg 77.74±33.91 87.56±28.09 75.53±35.02 0.342
PCO2, mmHg 40.18±9.63 42.22±7.31 39.73±10.10 0.488
BE, mmol/L 2.43±4.22 2.43±3.80 2.43±4.36 0.998
CHCO3-st, mmol/L 25.46±4.04 26.76±2.98 25.16±4.22 0.290
FiO2, 0.41±0.21 0.24±0.04 0.46±0.21 < 0.001
PaO2/FiO2, mmHg 236.28±142.07 385.70±155.85 202.67±116.39 < 0.001

Data are median (IQR), mean±SEM, n (%), or n/N (%). p values were calculated by Mann-Whitney U test, t test, χ2 test, or Fisher's exact test, as appropriate. HFNC, high-flow nasal catheter; NIV, non-invasive ventilation; IMV, invasive mechanical ventilation; ECMO, Extracorporeal Membrane Oxygenation.